Marylyn D. Ritchie

ARCHER-LD: Rapid Long-Range Linkage Disequilibrium Calculations at Biobank Scale using GPU Acceleration

Linkage disequilibrium (LD) information from one’s own dataset is considered optimal for downstream analyses such as statistical fine-mapping. However, the computational complexity ( computations for N variants) lead most studies to use external reference panels, such as from 1000 Genomes. To capture LD across all vari...