Marwan G. Althagafi

Arterial Resident But Not Monocyte-Derived Macrophages Require Endothelial CSF1.

BACKGROUND Tissue-resident macrophages (T-RMøs) accumulate at sites predisposed to atherosclerosis in the healthy aortic intima. T-RMøs require local cues for their maintenance, but the niche signals governing their persistence in arterial tissue remain poorly defined. Here, we identify distinct, spatially compartmenta...