Open access
Jul 2026
Trypanosomal MICOS is assembled on non-respiring mitochondrial crista precursors and associates with two integral microproteins
It is demonstrated that all MICOS subunits assemble onto precursor cristae, retaining conserved interactions with both outer and inner membrane protein machineries, establishing that MICOS assembly precedes cellular respiratory competence and expand its interaction landscape in trypanosomatids.
Michala Boudová, Teresa Wagner, Tomáš Bílý et al.
· bioRxiv · 1 citation