Genotoxic and cytokine-associated responses to benzo[g,h,i]perylene and benzo[b]fluoranthene in a human lung co-culture model at the pseudo-air-liquid interface.
Polycyclic aromatic hydrocarbons (PAHs), including benzo[g,h,i]perylene (BGP) and benzo[b]fluoranthene (BBF), are ubiquitous airborne pollutants with significant toxicological relevance. Inhalation represents the primary exposure route, with the respiratory epithelium and alveolar macrophages serving as key targets for...