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Author

Martina Brueckner

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Open access Oct 2026

Consecutive waves of NODAL inhibition are required for epiblast patterning

The mouse genome encodes two Lefty genes that antagonize NODAL signaling to break symmetry during gastrulation. Despite their central regulatory role, accurately describing and comparing their embryonic function remains unclear. Here, we generated high replicate powered single-cell transcriptional atlases of Lef...

Min-Ming Wang, T. Hou, JoAnne Villagrana et al. · 0 citations
Open access Jul 2026

Uniparental Disomy Reveals Hidden Genetic Causes of Congenital Heart Disease

TrioMix-UPD, an integrated short- and long-read sequencing framework for UPD detection and classification, is developed and established UPD as an underrecognized contributor to CHD.

Nahyun Kong, Javier Abello, Christopher J. Yoon et al. · 0 citations

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