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Author

Martina Bago Pilátová

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Oct 2026

Sphingofungin-based aminopolyols and DIX-like azasugars - their synthesis and in vitro biological profile.

A simple stereodivergent approach to sphingofungin-based aminopolyols and their modification into 1,5-dideoxy-1,5-iminoxylitol (DIX)-based 1-N-iminosugars was accomplished. The use of a [3,3]-heterosigmatropic rearrangement on carbohydrate scaffolds, followed by Grubbs metathesis chemistry, provided an efficient route...

Jana Špaková Raschmanová, Gabriela Ondrejkovičová, Martina Bago Pilátová et al. · 0 citations
Open access Sep 2026

A Novel Indole-Dihydroisoxazole Compound Activates Apoptotic, Mitochondrial and Autophagy-related Responses in Lymphoid and Myeloid Leukemia Cells.

Findings highlight the therapeutic potential of isoxazole-derived compounds, particularly DHI1, warranting further investigation in additional preclinical models and provide valuable insights into the molecular mechanisms underlying the antiproliferative effects of DHI1.

Monika Majirská, Zuzana Kudličková, M. Kello et al. · 0 citations

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