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Author

Martin Michaelis

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Open access Jan 2026

The HDAC Inhibitor Butyrate Reduces SOD1 Aggregation and Improves Motor Function in C. elegans and Cellular Models of ALS

It is demonstrated that sodium butyrate (NaB), a histone deacetylase inhibitor and microbial metabolite, ameliorates ALS‐related phenotypes in C. elegans and mammalian cell models expressing mutant isoforms of Sod1 linked to ALS.

Fiona Dresel, Martin Michaelis, C. Gourlay · 0 citations

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