Abstract A005: Preliminary results from STRIvE-01, Arm B: A phase I study of EGFR806 x CD19 CAR T cell immunotherapy for recurrent/refractory solid tumors in children and young adults
The epidermal growth factor receptor (EGFR) is associated with aggressive neoplastic disease, chemotherapy resistance, and increased metastatic potential in solid neoplasms. Approximately 20-30% of pediatric solid tumors (ST) express EGFR, enriched for soft tissue sarcomas (STS). The unique EGFR monoclonal antibody (...