Author

Markus Schepers

3 papers indexed here

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Review Aug 2026

Blinded sample size review for McNemar's test based on primary and surrogate endpoints

We develop blinded sample size re-estimation strategies for McNemar's test based on paired binary primary and secondary short-term surrogate endpoints. The development is motivated by a prospective randomized clinical trial on childhood glaucoma. A conditional power expression for McNemar's test given the primary endpo...

Markus Schepers, W. Brannath, Esther M. Hoffmann et al. · 0 citations

Open access Sep 2026

Proteomic Profiling of Post-COVID -19 Sequelae.

The emergence of Post-COVID sequelae (PCS) represents a global challenge. However, understanding of biological mechanisms and the definition of quantifiable risk factors remains limited. This study employed machine learning-based classification to explore the potential of proteomics in identifying associations with ind...

Sepehr Golriz Khatami, Rieke Baumkötter, T. Köck et al. · Molecular & Cellular Proteom... · 0 citations

Open access Sep 2026

Vocational factors and mental health during the COVID-19 pandemic in middle-aged and older adults: longitudinal evidence from a population-based cohort

The COVID-19 pandemic profoundly disrupted public health, social systems, and the workforce. This longitudinal study examines changes in depressive and anxiety symptoms before and during the pandemic in middle-aged and older adults (N = 6,813) from the Gutenberg Health and Gutenberg COVID-19 Study in Germany. Using rep...

T. Beutel, N. Hettich-Damm, Julia Petersen et al. · Frontiers in Public Health · 0 citations