Skip to content
Log in
Sponsored AI AM CLAUDE, A Beginner's Guide: Learn the basics of working with AI AI AM CLAUDE, A Beginner's Guide: Learn the basics of working with AI

Author

Markella Konstantinidou

View on Semantic Scholar

2 papers indexed here

We haven’t gathered this author’s papers yet. Follow them and we’ll fetch their work.

Not the right person? Other researchers publish under this name.

Open access Aug 2026

A Molecular Mechanistic Deep Dive into 14-3-3 Molecular Glue Cooperativity.

These findings establish cooperativity, intrinsic PPI affinity, and MG affinity as key parameters governing MG activity and selectivity, providing a framework for the rational design of MGs targeting hub protein interactomes.

Marloes A. M. Pennings, Edmee M. F. Vandenboorn-Bönner, Lisa Nooren et al. · 0 citations
Open access Sep 2026

C-RAF Sequence-Encoded Cooperativity Hotspots for 14-3-3/C-RAF Molecular Glues.

14-3-3 Proteins are hub proteins with an extensive interactome of phosphorylated client proteins, making them attractive targets for molecular glues (MGs) that stabilize specific 14-3-3/client protein complexes. However, selectively stabilizing individual 14-3-3 protein-protein interactions (PPIs) remains a key challen...

Marloes A. M. Pennings, G. Lauffer, Markella Konstantinidou et al. · 0 citations

We use cookies to run the site and, with your consent, for analytics and to show ads. See our Cookie Policy.