Andrographolide (AG) has been reported for its anticancer activity. However, it is classified as a class IV in the biopharmaceutics classification system (BCS). Therefore, AG possesses low bioavailability due to its low solubility and permeability. In this study, hyaluronic acid-coated chitosan nanoparticles (Hyalo-CS-...
Sohaila A. Shoala, H. Abbas, H. Elbedaiwy et al.· European journal of pharmace...· 0 citations
Alyrogenic index of plasma is independently and positively associated with MASLD, more degree of hepatic steatosis, insulin resistance and low adiponectin level, and using AIP alone or in combination with BMI could alarm clinicians to further investigate for presence of MASLD in individuals at outpatient clinics.
Manal Abdel-Mageed, Marium M. Shamaa, M. Labane et al.· Scientific Reports· 0 citations
The combination strategy may have the potential to achieve dose savings while maintaining efficacy comparable to the standard-dose SEM, through the enhancement of the antioxidant defenses, modulation of inflammation, and apoptosis, specifically via the modulation of the miR-34c/miR-155 and SIRT1/FOXO1 signaling.
Mohamed M. Zeweil, A. Khafaga, Marium M. Shamaa et al.· International Journal of Mol...· 0 citations
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