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Marina Müller Lupatini

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Open access Sep 2026

PSEN1 Expression Identifies a Developmentally Distinct Favourable‐Prognosis State in SHH α Medulloblastoma

Background Although PSEN1 is best known for its role in Alzheimer’s disease, it also regulates neural development and cerebellar morphogenesis. Medulloblastoma (MB) is the most common malignant pediatric brain tumor and arises from disrupted cerebellar developmental programs. The clinical significance of PSEN1 in MB re...

Julia Vanini, Amanda Thomaz, Marina Müller Lupatini et al. · 0 citations

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