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Author

M. Derieppe

2 papers indexed here

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Open access Oct 2026

AXL-directed antibody–drug conjugate therapy in soft-tissue sarcoma

AXL is a membrane-accessible receptor tyrosine kinase and a potential antibody–drug conjugate (ADC) target, but its therapeutic relevance in soft-tissue sarcoma remains incompletely defined. We evaluated the AXL-directed pyrrolobenzodiazepine ADC ADCT-601/mipasetamab uzoptirine using a sarcoma tissue microarray, patien...

N. El-Ghazzi, T. Sourisseau, V. Chaire et al. · 0 citations
Open access Oct 2026

Ebselen restores mitochondrial function through metabolic rewiring in Barth syndrome and related mitochondrial diseases.

Despite major advances in the genetic diagnosis of mitochondrial disorders, effective disease-modifying therapies remain scarce. Here, we identify ebselen (EBS) as a promising therapeutic candidate through a phenotypic drug screen in a yeast model of Barth syndrome, a cardiomyopathy caused by defective cardiolipin matu...

Claire Almyre, Anne-Louise Cayer, Nolwenn Bounaix et al. · 0 citations

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