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Mariana Moraes de Lima Perini

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Review Open access Sep 2026

Angiogenic and Osteogenic Strategies for Skeletal Regeneration in Aging

Aging disrupts skeletal homeostasis, resulting in impaired fracture healing, increased risk of nonunion, and reduced regenerative capacity. These deficits are associated with dysregulated inflammation, impaired angiogenesis, and reduced osteogenesis, while current treatments remain limited in aged populations. This rev...

Mariana Moraes de Lima Perini, Ji-Liang Li · 0 citations

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