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Author

Maria Kuznetsova

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Aug 2026

Dual knockdown of Scn1b and Gsdmd induces an M2-like functional state in macrophages and modulates inflammation and fibrosis in a rat model of acute respiratory distress syndrome

The potential use of adoptive transfer of siRNA-modified macrophages to influence the progression of ARDS is investigated and dual knockdown of Scn1b and Gsdmd leads to the formation of an M2-like macrophage phenotype in vitro.

Victoria V. Kiseleva, P. Vishnyakova, Anna Kosyreva et al. · 0 citations

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