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Author

Maria-José U. Ferreira

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Open access Sep 2026

Tryptoline urea derivatives for sensitizing resistant breast cancer cells to doxorubicin.

Co-administration of compound 9 with doxorubicin (DOX) significantly reduced fold resistance in MCF-7/DXR cells, almost restoring their sensitivity to levels similar to the parental cell line, and compound 9 acted synergistically with DOX, markedly increasing its cytotoxicity, associated with a strong increase in apopt...

Filipa Barbosa, Karankumar Balamurugan, N. R. Prasad et al. · 0 citations

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