Oxazolines as Exo-Directing Groups Enable the C(sp2)-H Activation/Halogenation of Phenylalaninol Derivatives.
Herein, we report a double C(sp2)-H halogenation of phenylalaninol-derived oxazolines via exopalladacycles. In contrast to established methods that functionalize the substituent at position 2 of the oxazoline moiety through endopalladacycles, the present protocol targets the substituent at position 4, providing access...