Open access
Aug 2026
A molecular switch for coordinating kinesin and dynein transport of mitochondrial cargo
A regulatory helix in the mitochondrial adaptor protein (TRAK) that mediates switching between kinesin- and dynein-driven transport is identified and reveals a molecular mechanism for coordinating the directional transport of mitochondria in response to intracellular signals.
C. Gladkova, Maria G Paez-Segala, W. Grant et al.
· Science · 2 citations