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Maria Francesca Astorino

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Review Open access Aug 2026

Decoding Synaptic Diversity: Molecular Architectures, Phase Transitions, and Shared Postsynaptic Failure in Alzheimer’s and Parkinson’s Disease

Synaptic failure is the most accurate pathological correlate of cognitive and motor decline in neurodegenerative diseases. However, the molecular logic governing selective synaptic vulnerability in Alzheimer’s (AD) and Parkinson’s (PD) remains a fundamental enigma. This review dissects the hierarchical organization of...

G. Cipriano, Ivan Anchesi, Alessia Floramo et al. · 0 citations

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