Open access
Sep 2026
A high-density CRISPR activation platform for mapping cancer dependencies and resistance pathways ex vivo and in vivo
Partita, a next-generation mouse whole-genome CRISPRa sgRNA platform, designed for unparalleled efficiency in gene activation studies, is introduced, unlocking new avenues for functional genomics and expanding the toolkit for discovering key drivers of biological processes across diverse research fields.
Sarah T. Diepstraten, Yexuan Deng, Margaret A. Potts et al.
· Science Advances · 0 citations