Maretoshi Hirai

Live-Cell Detection of Relative Intracellular Tension Dynamics Using Non-FRET α-Actinin and α-Catenin Tension Indicators

Molecular tension sensors enable the visualization of forces acting on specific intracellular proteins in living cells. Most established genetically encoded sensors rely on Förster resonance energy transfer (FRET), requiring donor–acceptor imaging and correction for spectral bleed-through, which can complicate their ap...