Author

Marcus Vetter

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Open access Aug 2026

Comparison of a Novel MRNA-Based Breast Cancer Subtyping Assay with PAM50 and Oncotype DX in Estrogen Receptor-Positive/HER2-Negative Breast Cancer: An Exploratory Age-Stratified Retrospective Cohort Study

Immunohistochemistry (IHC) of ER, PR, HER2, and Ki67 are established prognostic and predictive markers in breast cancer. Gene expression assays such as PAM50 and Oncotype DX are increasingly used for molecular subtyping and recurrence risk calculation. The APIS Breast Cancer Subtyping Kit (BCSK) quantitatively measures...

T. Wallrabenstein, E. Chiru, M. Sonderegger et al. · Current Issues in Molecular... · 0 citations

Open access Sep 2026

The liver niche accelerates, while the lung niche restrains secondary spread of breast cancer.

Breast cancer progression to visceral organs such as the lung and liver is associated with poor prognosis. Yet, these organs have diverse cellular microenvironments that may differentially influence cancer cell behavior. Here, we show that breast cancer metastases differ in their capacity for secondary seeding: the liv...

Magdalena K. Sznurkowska, Francesc Castro-Giner, Irene D'Anna et al. · Cancer Discovery · 0 citations