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Author

Marc Woodbury-Smith

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Open access Jul 2026

Transdiagnostic behavioral and sociodemographic influences on the cognitive-adaptive functioning gap in neurodivergent children.

Internalizing symptoms and social communication difficulties were most strongly associated with the cognitive-adaptive functioning gap, and SHAP analysis identified internalizing problems, social communication challenges, and OCD symptoms as the strongest predictors.

E. Wan, Melanie Penner, Jennifer Crosbie et al. · 1 citation
Open access Aug 2026

Neurabin I haploinsufficiency disrupts ion channel regulation and synaptic maturation in human cortical neurons in neurodevelopmental disorders.

The first comprehensive human mechanistic model of PPP1R9A haploinsufficiency using an isogenic CRISPR/Cas9-engineered iPSC system differentiated into cortical neurons is established, providing a human-specific mechanistic framework linking reduced Neurabin I dosage to neurodevelopmental and psychiatric disease risk.

Binte Zehra, Nesrin Mohamed, Richa Tambi et al. · 0 citations

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