Open access
Oct 2026
Structural basis for coupled DNA replication and uracil repair by a family of DNA polymerases from phages with T-modified genomes
Abstract Replicative DNA polymerases (DNAPs) play a critical role in genome duplication, ensuring the accurate transmission of genetic information in all domains of life. DNAPs are also essential for DNA viruses, as well as bacteriophages, where a uracil-DNA glycosylase (UDG) is often encoded in trans or is present in...
Sophia Missoury, S. Lucas-Staat, R. Sieskind et al.
· Nucleic Acids Research · 0 citations