Open access
Sep 2026
A novel 5-FU derivative chemotherapy: a promising pan-cancer treatment to improve antitumor efficacy and overcome therapy resistance
Mechanistically, EB-18 exerts multifaceted antitumor effects by disrupting the HSP27/DDX5 axis and DNA damage-response machinery, promoting DNA damage and apoptosis, while suppressing AKT/mTOR prosurvival signaling.
Quang Hieu Duong, E. Khusnutdinova, T. Le et al.
· Journal of Experimental &... · 0 citations