Author

Manuel Sánchez-Casalongue

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Review Open access Sep 2026

Closing the Diagnostic Gap in Early-Onset Colorectal Cancer: Red-Flag Symptoms, Screening, and Inherited Risk

Simple Summary Early-onset colorectal cancer is diagnosed before the age of 50, and its incidence is rising in many populations. Because most younger adults are not routinely offered screening, diagnosis usually follows the onset of symptoms. Rectal bleeding, persistent abdominal pain, sustained changes in bowel habits...

J. M. Martin-Moreno, L. Cabañas-Alite, I. Fernández-Benet et al. · Cancers · 1 citation

Review Open access Sep 2026

Understanding the Rising Incidence of Early-Onset Colorectal Cancer: Life-Course Determinants and Opportunities for Primary Prevention

Observational evidence does not establish that any single factor causes early-onset colorectal cancer or should independently determine screening eligibility, but the findings support prevention throughout the life course with healthier food and activity environments, tobacco control, reduced harmful alcohol use, and b...

A. Alegre-Martínez, L. Cabañas-Alite, I. Fernández-Benet et al. · Cancers · 1 citation