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Author

Manuel M. Müller

2 papers indexed here

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Open access Sep 2026

Substituting a conserved histidine alleviates difluoroacetate-dependent isoaspartate formation in a fluoroacetate dehalogenase

Organofluorides are ubiquitous in modern society, but their persistence poses significant environmental and health risks. Fluoroacetate dehalogenases (FAcDs) are promising candidates for the bioremediation of polyfluorinated substances, as they can hydrolyze C–F bonds efficiently under mild conditions. However, their a...

Suzanne C. Jansen, Luis F. Guerra, Cristina Duran et al. · 0 citations
Review Open access Jul 2026

Protein engineering: status report

Protein engineering appears to be entering a golden age, defined by a rapidly accelerating pace of progress, even as significant challenges in design, screening, and real-world application remain.

H. Ai, Frances H. Arnold, Doug Barrick et al. · 0 citations

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