Area Under the Curve-Guided Therapeutic Drug Monitoring of Mycophenolic Acid in Lung Transplant Recipients: Volumetric Absorptive Microsampling and Population Pharmacokinetic-Based Limited Sampling Strategies
Mycophenolate mofetil (MMF), a prodrug rapidly converted to mycophenolic acid (MPA), is widely used after lung transplantation, but fixed-dose therapy is complicated by exposure variability, enterohepatic recirculation, drug interactions, and limited routine use of area under the concentration-time curve (AUC)-guided t...