Intravenous Thrombolysis for Acute Ischemic Stroke Across Kidney Function.
BACKGROUND The effectiveness and safety of recombinant tissue-plasminogen activator (rt-PA; alteplase) for acute ischemic stroke in patients with low estimated glomerular filtration rate (eGFR) are uncertain. We evaluated whether the risks and benefits of rt-PA versus no rt-PA vary by eGFR category. METHODS We conduc...