Open access
Sep 2026
TRIM23 prevents adenovirus replication by p62-mediated selective autophagic degradation of viral E1A protein
The E3 ubiquitin ligase TRIM23 is involved in diverse cellular processes, however, its function in antiviral defense against adenovirus remains unclear. Here, we identify a novel mechanism by which TRIM23 restricts human adenovirus type 5 (HAdV-C5) replication. TRIM23 expression was upregulated upon HAdV-C5 infection,...
Nan Sun, Ji-Kai Zhang, Ban-Ruo Xia et al.
· PLoS Pathogens · 0 citations