Mamta F. Singh

Insulin resistance: A key player in the onset of diverse disease pathologies

Insulin is an endocrine peptide hormone involved in various physiological processes such as glucose uptake, lipid metabolism, cell growth and repair. Insulin resistance (IR) contributes to different biochemical abnormalities including inflammation, obesity, and prediabetes. IR is a condition associated with impairments...

Effect of hydroethanolic extract of Butea monosperma flower on bleomycin-induced pulmonary fibrosis in mice via IL-6 modulation

This study evaluates the antifibrotic and anti-inflammatory potential of a hydroethanolic extract of Butea monosperma flowers in bleomycin-induced pulmonary fibrosis in Swiss albino mice. The extract (100 and 200 mg/kg orally) was administered for 21 days following oropharyngeal aspiration of bleomycin (2.5 mg/kg) and...

In silico designing of small molecules for targeting RNA: current landscape and future directions