Aug 2026
Siglec-15 and PD-1 checkpoint blockade in combination with oncolytic Zika virus infection confers protection against immune-resistant gliomas.
Targeting Siglec-15, combined with PD-1 blockade and ZIKV overcomes myeloid immunosuppression and enhances T-cell activation in GBM, promoting durable anti-tumor immunity.
Ashwani Kesarwani, Amber Neil Griffith, Sonam Verma et al.
· Neuro-Oncology · 0 citations