Mai Nakashima

Identification of a sequence element regulating H3K9 methylation at the ap2-g locus in Plasmodium falciparum.

Plasmodium falciparum, the causative agent of malaria, undergoes a critical cell fate switch during the erythrocytic stage, when a subset of parasites exits asexual replication and differentiates into gametocytes-the forms required for transmission. This conversion is controlled by the transcription factor AP2-G, whose...