Plasmid-Resolved Metagenomics for Tracking Horizontal Transfer of Antimicrobial Resistance Determinants Across Microbial Communities
A critical assessment of the long-read assemblers such as hifiasm-meta, metaMDBG, metaFlye, HiCanu, and myloasm are carried out, finding that plasmids carrying AMR have a much wider range of phylogenetic host species than those that do not carry resistance, and thus form well-connected transmission networks across the...