Open access
Sep 2026
Tubulin E-Hook Hexamers Reveal Sequence-Dependent Compaction and Transient Secondary Structure Signatures
The present work shows that E-hook fragments possess functional structural differences governed by electrostatic interactions and sequence composition. The acidic C-terminal tails of tubulin, known as E-hooks, play a central role in regulating interactions between microtubules and motor proteins, microtubule-associated...
Alexander C. Bromley, Nicholas A. Kruse, Connor R. Brower et al.
· Molecules · 0 citations