Author

Madeleine M. Allen

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Open access Oct 2026

HIV-1 hijacks HGF/c-MET signaling to promote viral entry and replication in primary CD4+ T cells

ABSTRACT The mesenchymal-epithelial transition factor (c-MET) is a receptor tyrosine kinase best known for mediating hepatocyte growth factor (HGF) signaling in cancer, but its role in HIV-1 infection has remained unclear. Here, we identify c-MET as a host factor that promotes HIV-1 replication in CD4+ T cells by facil...

Shraddha Tripathi, Madeleine M. Allen, Li Wu · mBio · 0 citations