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Oct 2026

Clinical impact of prospective circulating tumour DNA testing for minimal residual disease in colorectal cancer: the INTERCEPT programme experience.

BACKGROUND The impact of circulating tumour DNA (ctDNA) detection, which informs minimal residual disease (MRD) after curative treatment, remains debated especially for stage IV patients. OBJECTIVE The study objectives were to evaluate the prognostic role of MRD and to estimate lead time (LT) at different timepoints...

G. Maddalena, K. Aziz, Ryan Sun et al. · 0 citations
Sep 2026

Abstract A043: Allele Specific Characteristics of KRAS Q61 Mutated Gastrointestinal Malignancies with Clinical Outcomes and Transcriptomic Features in Pancreatic Cancer

Pan-RAS and allele-specific inhibitors are entering clinical practice. Understanding KRAS-specific features is vital for therapy and overcoming resistance. We examined clinical and molecular traits of KRASQ61-mutated gastrointestinal cancers, especially pancreatic. Using Palantir Foundry, we queried surviv...

Sacha El Khoury, M. Yousef, Dan Zhao · 0 citations

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