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Author

M. Vosough

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#protein folding Open access Oct 2026

Computational Design and Structure-Guided Optimization of Anti-Osteopontin Monoclonal Antibodies at the Intersection of Obesity, Type 2 Diabetes, and Hepatocellular Carcinoma

Hepatocellular carcinoma (HCC) remains a leading cause of cancer-related mortality, and obesity and type 2 diabetes (T2D) are recognized metabolic risk factors for its development. In this study, disease-associated gene lists for T2D and obesity were integrated with differentially expressed genes from the Cancer Genome...

Elahe Shams, Elham Rismani, Pedram Asadi-Sarabi et al. · 0 citations
Review Open access Aug 2026

Immune reconstitution and tolerance-inducing therapies as promising therapeutic approaches in multiple sclerosis

This review reframes MS immunotherapy through a tolerance-centric paradigm, distinguishing continuous maintenance disease-modifying therapies (DMTs) from immune reconstitution therapies (IRTs) from immune reconstitution therapies (IRTs) and emerging antigen-specific tolerance strategies.

Alireza Beheshti Maal, M. Arki, Seyed Massood Nabavi et al. · 0 citations
Review Open access Aug 2026

Epigenetic Regulation of Liver Fibrosis: Mechanisms and Therapeutic Implications

This review summarizes the principal epigenetic changes involved in HSC activation, initiation/progression of liver fibrosis, and discusses recent interventions designed to modulate these epigenetic changes.

M. J. Tavaf, M. E. Varkiani, Saeid Abroun et al. · 0 citations

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