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M. V. van Gils

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Open access Sep 2026

Siglec-1-targeting single domain antibodies block or enhance pathogen binding to dendritic cells

High-affinity single domain antibodies, (also known as VHHs or Nanobodies) that allo- or orthosterically modulate ligand binding of Siglec-1 are identified and may serve as broad-spectrum pathogen blocking agents.

H. J. Brink, A. Affandi, S. Man et al. · 0 citations

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