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The authors' findings reveal separable effects on TLR trafficking, downstream signalling and inflammasome activation, identifying CNPY3 as a key regulator of multiple cellular pathways involved in inflammatory responses and neurodevelopment.
Objective: To determine the psychosocial and economic burden of the caregivers of cancer patients. Study Design: Cross-sectional study. Place and Duration of Study: Department of Medical Oncology, PNS Shifa Hospital, Karachi Pakistan, from Jun to Dec 2025. Methodology: A total of 150 caregivers of cancer patients were...
BACKGROUND The BORCS5 is an important and critical component of the BLOC-one-related complex (BORC), involved in kinesin-dependent anterograde lysosomal transport. Aberrations in the octameric protein complex encompass lethal neurological manifestations, such as arthrogryposis multiplex congenita, brain malformations a...
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