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Sponsored Design Multi-Agent AI Systems Using MCP and A2A: Engineer your own Pyt Design Multi-Agent AI Systems Using MCP and A2A: Engineer your own Pyt

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M. Ubbink

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Open access Sep 2026

Conserved Asp233–Asp246 hydrogen bond modulates active site dynamics in class A β‐lactamases

Rigid enzymes catalyze chemical reactions by stabilizing the transition state through a specific conformation. Catalytic residues are precisely positioned, and enzyme dynamics are kept to a minimum. It is thought that conserved residues around the active site (second‐shell residues) play a crucial role in positioning c...

Cristina V. Lopez-Gallego, Monika Timmer, J. Vreede et al. · 0 citations

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