FcγR-mediated antibody-dependent enhancement of SARS-CoV-2 infection in human monocyte-derived macrophages
Macrophages play a central role in innate immunity but can also facilitate viral dissemination through antibody dependent mechanisms, and, in turn drive the severity of the clinical symptomatology. Although macrophages are generally considered non permissive to SARS-CoV-2, anti-Spike antibodies may mediate virus ce...