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M. Svoboda

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Review Open access Aug 2026

Polygenic risk score and its role in cancer susceptibility.

This review summarizes the principles of PRS, the main sources of variability between models, and its potential applications in risk stratification and personalized cancer screening and addresses limitations in transferability, the need for calibration, and the currently limited evidence for improvements in hard clinic...

Adéla Mišove, E. Macháčková, Klára Nováková et al. · 0 citations

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