Author

M. Suchard

3 papers indexed here

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Preprint Aug 2026

Stable Matrix Parametrizations and Structured Adjoints for Ornstein-Uhlenbeck Processes

Ornstein-Uhlenbeck processes with flexible multivariate drift matrices are powerful models for capturing coupled, asymmetric, and damped-oscillatory mean reversion. However, likelihood-based inference is challenging because the drift matrix must remain Hurwitz stable, while likelihood and gradient evaluations require r...

F. Monti, A. Holbrook, N. Glatt-Holtz et al. · 0 citations

Preprint Sep 2026

An adaptive time-tree transition kernel for Bayesian phylogenetic inference

Bayesian phylogenetic and phylodynamic analyses can be very time-consuming, owing to the combination of complex models that are used to estimate key parameters from increasingly large genomic data sets and their associated metadata. The use of high-performance computer hardware can -- to a certain extent -- alleviate t...

M. Brusselmans, Guy Baele, S. Hong et al. · 0 citations

Open access Aug 2026

Comparative Effectiveness of Ticagrelor vs. Prasugrel in Patients with Acute Coronary Syndrome Undergoing Percutaneous Coronary Intervention

Background: Ticagrelor and prasugrel are recommended P2Y12 inhibitors for patients with acute coronary syndrome (ACS) undergoing percutaneous coronary intervention (PCI), yet uncertainty persists regarding their direct comparative evidence and guideline recommendations differ. Methods: We conducted a multinational retr...

C. Han, A. Ostropolets, C. Blacketer et al. · medRxiv · 0 citations