Tobacco smoking has a strong influence on DNA methylation (DNAm), enabling the development of DNAm-based smoking predictors, yet external evaluations of these have remained limited. We aimed to assess six DNAm-based smoking predictors in a large sample of middle-aged and older Australians for (i) their accuracy and rel...
Xiao-Yu Fan, D. L. Li, Allison M. Hodge et al.· International Journal of Can...· 0 citations
The gut microbiome has been linked to cancer in many cross-sectional studies. These studies compared individuals with and without cancer, but they do not establish causation. Prospective cohort studies, with faecal samples collected before a cancer diagnosis, will be instrumental in assessing the role of the gut microb...
E. Vogtmann, Caroline Y. Um, S. Zouiouich et al.· The Lancet Microbe· 0 citations
A comprehensive analysis of 60 CIMs provides limited evidence supporting broad causal effects of circulating inflammatory markers contributing to variation in MD phenotypes, although most instruments demonstrated weak conditional instrument strength after inclusion of BMI.
A. H. Suger, T. Harrison, C. Haas et al.· medRxiv· 0 citations
This investigation investigated whether selective integration of lipidomic and genomic risk signals into AusCVDRisk improves 5-year CVD prediction and reclassification, with a focus on individuals at intermediate clinical risk.
Aleksandar Dakic, Jing-Qin Wu, Ting-Ting Wang et al.· EClinicalMedicine· 0 citations
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