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M. Sioud

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2 papers indexed here

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#protein folding Open access Oct 2026

N1-Methylpseudouridine-Modified mRNA-Transfected Dendritic Cells Enable Efficient Generation of Functional Tumor Antigen-Specific Cytotoxic T Lymphocytes

It is demonstrated that m1Ψ modification substantially enhances antigen expression and supports the efficient generation of functional, antigen-specific CTLs, providing a promising platform for next-generation mRNA-based cancer vaccines and adoptive T-cell therapies.

Tiffany Chor Kiu Ngan, M. Sioud · 0 citations
Review Open access Oct 2026

Molecular basis for developing tumor-targeted siRNAs for future immunotherapy.

By silencing genes involved in immune suppression, siRNAs can restore T cell activation and improve the efficacy of cancer vaccines and adoptive cell therapies, however, significant challenges remain.

M. Sioud · 0 citations

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