Review
Open access
Oct 2026
Recent advances in the synthesis, structural diversification, and biological evaluation of sulfamethoxazole derivatives
Sulfamethoxazole is a clinically important sulfonamide antibiotic that remains a valuable pharmacophore in medicinal chemistry due to its established antibacterial activity and structural versatility. However, the emergence of antimicrobial resistance and limitations related to solubility, pharmacokinetics, and safety...
Ahmed H. M. Elwahy, M. Shaaban, Ismail A. Abdelhamid
· RSC Advances · 0 citations