Longitudinal 1H NMR metabolomics of serum in a chronic temporal lobe epilepsy model reveals systemic metabolic remodeling
Introduction Temporal lobe epilepsy is associated with systemic metabolic alterations that may evolve during disease progression and in response to pharmacological treatment. This study employed a longitudinal 1H NMR-based metabolomics approach to characterize the serum metabolic profile of a chronic pilocarpine-induce...