Crimean-Congo hemorrhagic fever virus (CCHFV) is a WHO-priority pathogen with high mortality and wide global distribution. A major challenge in CCHFV vaccine development is identifying antigens that induce functional cellular and humoral immunity. We previously showed that the CCHF nucleoprotein (NP) elicits protective...
Jing-Yi Yan, Lara Sweetapple, Christian An Bính Nordentoft et al.· bioRxiv· 0 citations
Vaccines have been a cornerstone of human health for more than 200 years and one of the most important tools to reduce childhood deaths caused by pathogens. The concept of vaccines is basically to take something safe, make it immunogenic and induce an immune response in the host that will protect it against something d...
This integrated profiling approach identifies targetable pathways, surface antigens, and neoantigens in pDMG, supporting the development of CAR-T and TCR-T therapies and suggest potential applicability to other cancers harboring shared mutations.
G. Rovesti, Alejandro Fernandez Woodbridge, Haidong Yao et al.· Neuro-Oncology Advances· 0 citations
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