M. S. Unger

The Impact of a Short-Term Reduction in CD8+ T Cells on Aged APP/PS1 Mice

CD8⁺ T cells infiltrate the brain parenchyma of patients with Alzheimer’s disease (AD), where they localize near microglia and neurons. Although recent studies have revealed that they can clonally expand and possess a unique phenotype, their contribution to disease pathogenesis remains poorly understood. To investi...